Activity for Natural Selection and Adaptation

Photo of a pocket mouse being held by a researcher

This film uses the rock pocket mouse as a living example of Darwin’s process of natural selection. It highlights the research of Michael Nachman, who has quantified predation on rock pocket mice and identified adaptive changes in coat-color genes that allow the mice to travel under the radar of hungry predators.

The “Student Handout” probes students’ understanding of the key concepts addressed in the film. The “Educator Materials” document provides suggested pause points in the film with questions for students, background information, and detailed discussion points; a list of related resources and references; and an answer key for the “Student Handout.”

The “Resource Google Folder” link directs to a Google Drive folder of resource documents in the Google Docs format. Not all downloadable documents for the resource may be available in this format. The Google Drive folder is set as “View Only”; to save a copy of a document in this folder to your Google Drive, open that document, then select File → “Make a copy.” These documents can be copied, modified, and distributed online following the Terms of Use listed in the “Details” section below, including crediting BioInteractive.

Student Learning Targets

Details

Estimated Time

Two 50-minute class periods.

Key Terms

camouflage, melanin, melanocortin 1 receptor (MC1R), mutation, rock pocket mouse, selective pressure, trait, variation

Primary Literature

Hoekstra, Hopi E., Kristen E. Drumm, and Michael W. Nachman. “Ecological Genetics of Adaptive Color Polymorphism in Pocket Mice: Geographic Variation in Selected Neutral Genes.” Evolution 58, 6 (2004): 1329–1341. https://doi.org/10.1111/j.0014-3820.2004.tb01711.x.

Hoekstra, Hopi E., J. G. Krenz, and Michael W. Nachman. “Local Adaptation in the Rock Pocket Mouse (Chaetodipus intermedius): Natural Selection and Phylogenetic History of Populations.” Heredity 94, 2 (2005): 217–228. https://doi.org/10.1038/sj.hdy.6800600.

Nachman, Michael W., Hopi E. Hoekstra, and Susan L. D’Agostino. “The Genetic Basis of Adaptive Melanism in Pocket Mice.” Proceedings of the National Academy of Sciences USA 100, 9 (2003): 5268–5273. https://doi.org/10.1073/pnas.0431157100.

Terms of Use

The resource is licensed under a Creative Commons Attribution-NonCommercial-ShareAlike 4.0 International license. No rights are granted to use HHMI’s or BioInteractive’s names or logos independent from this Resource or in any derivative works.